Several medical conditions can make Silditop 100 mg less effective in treating erectile dysfunction (ED). Since Silditop works by increasing blood flow to the penis, any disease that affects blood flow, nerve function, or hormone levels may reduce its effectiveness.
Diabetes is a leading cause of Silditop 100 mg and can damage both blood vessels and nerves, making it harder for Sildenafil to work properly. Similarly, high blood pressure and heart disease affect circulation and may reduce the drug’s effectiveness. Atherosclerosis (narrowing of the arteries) can also limit blood flow to the penis, weakening the impact of the medication.
Hormonal disorders such as low testosterone (hypogonadism) may cause ED that doesn’t respond well to Sildenafil alone. Neurological conditions like multiple sclerosis, Parkinson’s disease, or spinal cord injuries interfere with nerve signals necessary for erections.
Psychological issues, including severe anxiety, depression, or relationship problems, can also prevent the drug from working even if blood flow is improved.
Additionally, liver or kidney disease can affect how the body processes the medication, reducing its potency or increasing side effects. In all cases, proper diagnosis and treatment of the underlying condition are important to improve Silditop’s effectiveness.