In case you are allergic to sildenafil or another ingredients of Manforce 100 mg pill.if you be afflicted by any heart problems like stroke or heart attack or any liver issues.in case you are taking riociguat that is used within the treatment of arterial blood pressure.in case you are taking positive drugs (nitrates) that could result in a decrease in blood pressure.when you have ever had a lack of vision.if you have a sure eye circumstance like retinitis pigmentosa.