Men who have erectile dysfunction and are at least 18 years old can take tadalafil. The most common dosage of tadalafil that is administered is 60 mg. It is quite likely that you will be prescribed this dosage if this is your first experience taking Tadalafil. Tadalafil should be taken around an hour before you want to have sex. Tadalista 60 is usually started at one hour before sexual activity, once a day.