Yes, there are significant risks associated with taking Malegra Professional (which contains Sildenafil citrate) together with nitrates (commonly prescribed for chest pain or angina). Combining these two medications can lead to a dangerous and potentially life-threatening drop in blood pressure.
Sildenafil (PDE5 inhibitor): Malegra Professional works by increasing blood flow to the penis, primarily by inhibiting the enzyme phosphodiesterase type 5 (PDE5), which promotes the relaxation of blood vessels and increases blood flow.
Nitrates: Medications like nitroglycerin, isosorbide mononitrate, and isosorbide dinitrate are prescribed to treat heart conditions like angina by dilating blood vessels, thus improving blood flow to the heart and reducing chest pain.
When Sildenafil and nitrates are taken together, they both work to relax and dilate blood vessels, which can lead to a severe drop in blood pressure (hypotension).
Avoid combining Malegra Professional and nitrates at all costs. If you are taking nitrates for any heart condition, you should not take Sildenafil or any similar PDE5 inhibitor for erectile dysfunction.
Consult a doctor: Always inform your healthcare provider about all the medications you're taking to avoid potential interactions. Your doctor may suggest alternative ED treatments that don't pose the same risk.
In summary, Sildenafil and nitrates should never be used together due to the high risk of life-threatening side effects caused by extreme drops in blood pressure. Always consult with your doctor before combining medications.
