But all those studies were very small, and not all research on the keto diet is as promising. One American Society for Clinical Nutrition May 2006 study of 20 participants found that those on the diet didn’t lose more weight than those on a Keto Wave....maisBut all those studies were very small, and not all research on the keto diet is as promising. One American Society for Clinical Nutrition May 2006 study of 20 participants found that those on the diet didn’t lose more weight than those on a Keto Wave. But they did have fouler moods and higher levels of inflammation, which has been linked to a variety of conditions, including heart disease and cancer.